Searchable abstracts of presentations at key conferences in endocrinology

ea0081p606 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

The ecology of the microbiome in children with congenital generalized lipodystrophy type 4 (CGL4) is quickly modified after metreleptin treatment

Daffara Tommaso , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Massa Nadia , Caramaschi Alice , Mignone Flavio , Romanisio Martina , Rabbone Ivana , Giordano Mara , Aimaretti Gianluca , Bona Elisa , Prodam Flavia

Introduction: Lipodystrophy syndromes are characterized by a progressive metabolic impairment secondary to adipose tissue dysfunction and genetic background. The role of microbiota is still uninvestigated.Objective: Evaluate the gut microbiome ecology in relation to dietary and clinical parameters in two infant siblings with congenital generalized lipodystrophy type 4 (CGL4) before and after treatment with recombinant leptin.Method...

ea0070aep373 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

The educational training to the Mediterranean diet-like pattern is followed by improvement in cardiometabolic parameters and ecology of the microbiome in children with obesity: Preliminary results of the GOOD DAY trial

Ricotti Roberta , Archero Francesca , Landoni Valentina , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Solito Arianna , Novello Giorgia , Gamalero Elisa , Mignone Flavio , Cavaletto Maria , Agosti Emanuela , Bona Elisa , Prodam Flavia

Introduction: In the pediatric population the progression of obesity-related diseases can be delayed or prevented through changes in lifestyle, including the promotion of a Mediterranean-like dietary (MD) pattern.Objective: We aimed to assess the efficacy of an educational training to MD based on gamification with respect to a conventional weight-loss treatment in obese pediatric subjects on weight decreased and cardiometabolic risk factors (GOOD-DAY Tri...

ea0073aep166 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

The ecology of the microbiome in children with obesity is associated to insulin resistance anddiet composition

Ricotti Roberta , Archero Francesca , Landoni Valentina , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Solito Arianna , Antoniotti Valentina , Gamalero Elisa , Massa Nadia , Mignone Flavio , Cavaletto Maria , Agosti Emanuela , Bona Elisa , Prodam Flavia

IntroductionIn the pediatric population, the progression of obesity-related diseases can be delayed or prevented through lifestyle changes, including the promotion of a Mediterranean-like dietary (MD) pattern.ObjectiveWe aimed to evaluate the gut microbiome ecology in relation to dietary and clinical parameters in the pediatric subjects with obesity recruited at baseline in a protocol on an educational traini...